Official Cisne Calculator

The Official Cisne Calculator is a specialized tool designed for healthcare professionals to assess the risk of serious complications in patients with chemotherapy-related febrile neutropenia. Developed through a robust, data-driven process across multiple hospitals, this application aims to pinpoint initially stable-appearing patients who might develop severe complications during the progression of their febrile condition.

Febrile neutropenia, a potential side effect of chemotherapy, poses a significant risk as it may escalate quickly and unexpectedly. The app evaluates indicators such as acute organ failure, septic shock, hypotension, severe infections, and other critical factors within the first three hours post-diagnosis. Patients with conditions like acute leukemia or those who have undergone significant treatments like bone marrow transplants are not included in this assessment tool.

It is important to note that while the app provides estimation of risk based on initial clinical stability, it does not replace clinical judgment or propose specific management strategies. Neither is it designed for selecting low-risk patients for outpatient care until further validated by clinical trials. Healthcare providers are advised to use this tool as an aid to enhance, not replace, their clinical evaluations.

The Official Cisne Calculator distinctly emphasizes the need for immediate medical intervention for febrile neutropenia and discourages its use as a substitute for professional advice. Reliance on its predictions is at the user’s discretion, and it comes with a caution to always consider unusual risk factors that might affect a minority of patients.

The Official Cisne Calculator serves as a critical, supportive tool in the early identification of severe risks in febrile neutropenia patients, reinforcing the need for vigilant and informed clinical decision-making.